Turnaround times
The quoted turnaround time is from sample receipt in the laboratory, to results authorisation in the Laboratory Information Management system. The times do not include transport of specimen to the laboratory or the administrative process to print and post/email reports. Service users must allow for transport and reporting time when ordering tests.
Clinical background:
Blood group genotype testing for multitransfused, DAT positive patients or patients receiving targeted therapy with monoclonal antibodies when serological phenotyping cannot be performed. The genotype can be used to predict blood group phenotype.
Molecular genotyping allows the determination of RhD, C, c, E, e, Cw, M/N, S/s, Kk, Jka/b, Fya/b, Doa/b, U-, Uvar and more.
Specimen container paediatric:
1mL EDTA or 6mL EDTA
Specimen container adult:
6mL K2 EDTA (pink top)
Minimum volume paediatric:
1mL
Minimum volume adult:
6mL
Special requirements:
Molecular genotyping cannot be ordered through PowerChart. Samples are referred to the regional reference centre by the Transfusion laboratory as part of ongoing investigations.
Sample stability:
Short term storage: 24 hours at room temperature.
Transport requirements:
Sample should be transported to Laboratory Medicine Reception via GP courier, hospital air-tube system or hand delivered to maintain storage conditions. Samples must not be subjected to extreme hot or cold conditions prior to testing.
Add on test:
N/A
Interpretation:
The molecular genotype report will state the blood group antigens identified through genetic analysis.
Factors affecting result:
Samples which are old (>24 hours). Incorrect specimen type received. Clotted, haemolysed, icteric or lipaemic samples. Insufficient plasma provided.
Other info:
This test is referred to NHSBT by the Transfusion laboratory.