Turnaround times
The quoted turnaround time is from sample receipt in the laboratory, to results authorisation in the Laboratory Information Management system. The times do not include transport of specimen to the laboratory or the administrative process to print and post/email reports. Service users must allow for transport and reporting time when ordering tests.
Clinical background:
SmRNP antibodies may help in the differentiation of connective tissue diseases. In SLE SmRNP antibodies may occur in conjunction with antibodies to ds-DNA and Sm. When SmRNP antibodies occur alone they point to a diagnosis of undifferentiated connective tissue disease (UCTD).
Specimen container paediatric:
Serum-Plain tube
Specimen container adult:
Serum-SST
Minimum volume paediatric:
0.5 ml
Minimum volume adult:
1 ml
Special requirements:
None
Availability:
SmRNP Antibodies are detected by BioPlex 2200 multiplex analyser and are run on a daily basis.
Freq analysis:
Daily
Add on test:
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to [email protected]
Quality assurance:
UK NEQAS for Antibodies to Nuclear and Related Antigens
Interpretation:
There is no relationship between the titre of anti-RNP antibody and disease activity.
Reference ranges:
Normal Range: Negative
Other info:
SmRNP antibodies are detected as part of the ANA and Related antibodies assay and are reported as Negative or Positive.