Turnaround times
The quoted turnaround time is from sample receipt in the laboratory, to results authorisation in the Laboratory Information Management system. The times do not include transport of specimen to the laboratory or the administrative process to print and post/email reports. Service users must allow for transport and reporting time when ordering tests.
Clinical background:
Scl-70 antibodies are found in 20-40% of patients with diffuse cutaneous systemic sclerosis. Patients with these antibodies are said to develop particularly severe skin disease, musculoskeletal disease and cardiopulmonary disease.
Specimen container paediatric:
Serum-Plain tube
Specimen container adult:
Serum-SST
Minimum volume paediatric:
0.5 ml
Minimum volume adult:
1 ml
Special requirements:
None
Availability:
Scl-70 Antibodies are detected by BioPlex 2200 multiplex analyser and are run on a daily basis.
Freq analysis:
Daily
Add on test:
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to [email protected]
Quality assurance:
UK NEQAS for Antibodies to Nuclear and Related Antigens
Interpretation:
None
Reference ranges:
Normal Range: Negative
Other info:
Scl-70 antibodies are detected as part of the ANA and Related antibodies assay (BioPlex) and are reported as Negative or Positive. Samples giving results in an internally defined borderline range are retested using another method (Immunoblotting) to give a definitive result and this is reported as Negative, Borderline, Positive, or Strongly positive.