Turnaround times
The quoted turnaround time is from sample receipt in the laboratory, to results authorisation in the Laboratory Information Management system. The times do not include transport of specimen to the laboratory or the administrative process to print and post/email reports. Service users must allow for transport and reporting time when ordering tests.
Clinical background:
Protein C is one of the natural anticoagulants. It is a vitamin dependant plasma glycoprotein and binds to thrombomodulin with Protein S as a co-factor to inactivate Factors Va and VIIIa. Deficiencies in Protein C lead to an increased thrombotic risk. It is assayed as part of the Thrombophilia Screen.
Specimen container paediatric:
Light blue – sodium citrate
Specimen container adult:
Light blue – sodium citrate
Minimum volume paediatric:
5.2mL
Minimum volume adult:
10.8mL
Special requirements:
Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.
Sample stability:
4 hrs
Transport requirements:
Samples should be transported to lab without delay
Freq analysis:
Weekly
Add on test:
[email protected] (external)
Quality assurance:
UK NEQAS Blood Coagulation
Reference ranges:
79 – 150IU/dL
Note: For Haemostatic tests, paediatric reference ranges may be different to adult ranges.
Quantitative assay of functional protein C as part of a thrombophilia screen.