Turnaround times
The quoted turnaround time is from sample receipt in the laboratory, to results authorisation in the Laboratory Information Management system. The times do not include transport of specimen to the laboratory or the administrative process to print and post/email reports. Service users must allow for transport and reporting time when ordering tests.
Clinical background:
Paraneoplastic neurological syndromes (PNS) are a group of neurological disorders associated with a tumour and its metastasis that are not the cause of the syndromes. An autoimmune process is considered as the underlying pathophysiological mechanism. Specific anti-neuronal autoantibodies can be detected in a majority of patients with PNS. These include Anti-Hu, Anti-Yo, Anti-Ri, Anti-CRMP5, Anti-Amphiphysin, anti Ma-1, anti-Ma-2, anti-Sox1, anti-Tr, anti-Zic4 and anti-GAD65 antibodies.
Specimen container paediatric:
Serum – SSTCSF in universal
Specimen container adult:
Serum – SSTCSF in universal
Minimum volume paediatric:
0.5ml
Minimum volume adult:
0.5ml
Special requirements:
none
Freq analysis:
weekly
Add on test:
All urgent add ons via telephone on 0191 282 1890, and must be confirmed via email to the appropriate email address [email protected]
Reference ranges:
Normal Range for all above antibodies: Negative
Other info:
All paraneoplastic Immunoblots are reported as Negative, Equivocal or Positive.