Turnaround times
The quoted turnaround time is from sample receipt in the laboratory, to results authorisation in the Laboratory Information Management system. The times do not include transport of specimen to the laboratory or the administrative process to print and post/email reports. Service users must allow for transport and reporting time when ordering tests.
Clinical Background:
Antibiotic resistance among Gram-negative bacteria is increasingly problematic. In some instances, no single antibiotic can be identified to treat serious infections. Our Microbiology department can perform Multiple Combination Bactericidal Testing (MCBT) to identify combinations of antibiotics that might be used for effective therapy. This test can be performed on a range of Gram-negative species that are associated with antibiotic resistance including Enterobacterales (for example, E. coli and Klebsiella) as well as resistant strains of Pseudomonas, Burkholderia, Stenotrophomonas and Acinetobacter.
Specimen Container Paediatric:
Bacterial isolate on an agar slope.
Specimen Container Adult:
Bacterial isolate on an agar slope.
Minimum Volume Paediatric:
N/A
Minimum Volume Adult:
N/A
Special Requirements:
Send samples to laboratory using national category B transport recommendations.
Sample Stability:
N/A
Transport Requirements:
Category B UN3373 regulations.
Add On Test:
N/A
Quality Assurance:
External Quality Assurance Scheme: Not available for this test.
Interpretation:
Interpretative comments are added to reports where applicable
Reference Ranges:
N/A
Factors Affecting Result:
If delays likely, refrigerate at 2-8 deg C
Referenced Documents:
Methodology based on that described in Lang et al. 2000. Am J Respir Crit Care Med 162, 2241-2245 and Aaron et al. 2000. Am J Respir Crit Care Med 161, 1206-1212. Test breakpoints based on EUCAST guidelines: https://www.eucast.org/clinical_breakpoints
Other Info:
N/A