Turnaround times
The quoted turnaround time is from sample receipt in the laboratory, to results authorisation in the Laboratory Information Management system. The times do not include transport of specimen to the laboratory or the administrative process to print and post/email reports. Service users must allow for transport and reporting time when ordering tests.
Clinical background:
The Methylation EPIC Array is able to quantify methylation by targeting significant sites across the whole genome for the detection of genome-wide copy number changes (gains/losses/gene amplifications) and loss of heterozygosity (LOH). These genomic changes can help in the diagnosis and prognosis of haematological malignancies. This technique is performed on material from FFPE.
Specimen container paediatric:
FFPE for tissue biopsies
Specimen container adult:
FFPE for tissue biopsies
Minimum volume paediatric:
5 × 10 µM curls
Minimum volume adult:
5 × 10 µM curls
Special requirements:
Please complete NEHODS request form
Sample Stability:
N/A
Transport requirements:
Samples should be sent to laboratory immediately.
Freq Analysis:
Daily
Add On Test:
Can be added to any genetics sample where DNA has been stored
Quality Assurance:
UK NEQAS
Interpretation:
By genetics clinical scientist
Reference Ranges:
N/A
Factors Affecting Result:
Quality and size of sample
Referenced Documents:
N/A
Other Info:
This provides information at a lower resolution than SNP Array but can be more successful than this on FFPE material.