Turnaround times
The quoted turnaround time is from sample receipt in the laboratory, to results authorisation in the Laboratory Information Management system. The times do not include transport of specimen to the laboratory or the administrative process to print and post/email reports. Service users must allow for transport and reporting time when ordering tests.
Clinical background:
This is a serological assay used to detect IgM antibodies to hepatitis B virus (HBV) core antigen and is a marker of acute hepatitis B virus infection. Automatically tested by the laboratory in all new Hepatitis B Virus surface antigen (HBsAg) positive samples. IgM is usually detectable for around 3 months after acute infection. In patients with chronic HBV infection IgM can remain detectable or be detected intermittently.
Specimen container paediatric:
Clotted blood.
Specimen container adult:
Clotted blood – Gold SST.
Minimum volume paediatric:
1ml
Minimum volume adult:
5ml
Special requirements:
Send to laboratory as quickly as possible. If delays likely, refrigerate at 2-8 deg C.
Sample stability:
Stable for up to 24 hrs.
Transport requirements:
Standard
Add on test:
Possible up to 5 days.
Quality assurance:
UK National External Quality Assurance Scheme (UKNEQAS)
Interpretation:
Detectable hepatitis B core IgM antibody typically indicates recently aquired hepatitis B infection.
Reference ranges:
None available
Factors affecting result:
If delays likely, refrigerate at 2-8 deg C.
Referenced Documents:
Standards of Microbiology Investigations (UK SMI V4)
Other info:
Acute hepatitis B is a notifiable infection and should be communicated to the local health protection team.