Turnaround times
The quoted turnaround time is from sample receipt in the laboratory, to results authorisation in the Laboratory Information Management system. The times do not include transport of specimen to the laboratory or the administrative process to print and post/email reports. Service users must allow for transport and reporting time when ordering tests.
Clinical background:
This is a calculated parameter derived from the PT reaction and is used as part of the clotting screen. When a clot forms in anticoagulated plasma, there is a change in state caused by the precipitation of soluble fibrinogen being converted to fibrin which precipitates and cross links with more fibrin forming a clot. The change in state can be followed by a number of coagulation analysers where it is seen as a reduction in light transmission through the test cuvette.The change is then converted into a concentration of Fibrinogen by use of a calibration curve prepared from plasma with a known fibrinogen concentration. This measurement is not applicable in cases where there is on-going fibrinolysis (acute DIC or Fibrinoyltic therapy) but will give an indication of the Fibrinogen level in the majority of cases.
Specimen container paediatric:
Light blue – sodium citrate
Specimen container adult:
Light blue – sodium citrate
Minimum volume paediatric:
1.3mL
Minimum volume adult:
2.7mL
Special requirements:
Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.
Sample stability:
24 hrs
Transport requirements:
Samples should be transported to lab without delay.
Freq analysis:
Continuous
Add on test:
[email protected] (external)
Quality assurance:
UK NEQAS Blood Coagulation
Reference ranges:
Fibrinogen (derived) 2.1 to 4.8g/L
Other info:
As part of a coagulation screen.