Clinical background:
Antibodies to NR1 and NR2 have been associated with a limbic encephalitis, SLE and variant epilepsies. There is an association with ovarian or mediastinal teratomas expressing the NMDA receptor, although cases may occur without any evidence of malignancy.
Specimen container paediatric:
Serum-Plain tube
Serum or CSF
Specimen container adult:
Serum-SST
Minimum volume paediatric:
0.5 ml
Minimum volume adult:
1 ml
Special requirements:
None
Availability:
Analysed once per week
Add on test:
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address [email protected]
Quality assurance:
IfQ autoantibodies against Neuronal antigens
Reference ranges:
Normal Range: Negative.
Other info:
Reported as Negative or Positive