Clinical background:
They are found in 70-80% of cases of limited cutaneous scleroderma (CREST syndrome).
Specimen container paediatric:
Serum-Plain tube
Specimen container adult:
Serum-SST
Minimum volume paediatric:
0.5 ml
Minimum volume adult:
1 ml
Special requirements:
None
Freq analysis:
Daily
Add on test:
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address [email protected]
Quality assurance:
UK NEQAS for Antibodies to Nuclear and Related Antigens
Interpretation:
None
Reference ranges:
Normal Range: Negative
Other info:
Centromere antibodies are requested as part of the ANA and related antibodies test but are detected on HEp-2 substrate as part of the Autoantibody Screen .